ZB K 35008-1990 防爆挠性连接管
作者:标准资料网 时间:2024-05-14 18:18:33 浏览:8932
来源:标准资料网
基本信息
标准名称: | 防爆挠性连接管 |
中标分类: |
电工 >>
低压电器 >>
防爆电器 |
替代情况: | 被JB 9600-1999代替 |
发布日期: | |
实施日期: | 1991-01-01 |
首发日期: | |
作废日期: | |
出版日期: | |
适用范围
没有内容
前言
没有内容
目录
没有内容
引用标准
没有内容
所属分类: 电工 低压电器 防爆电器
【英文标准名称】:StandardGuideforMeasuringthePresenceofPlanarOrganicCompoundsWhichInduceCYP1A,UsingReporterGeneTestSystems
【原文标准名称】:用指示器基因测试系统测定感应CYP1A的共面有机化合物的存在的标准指南
【标准号】:ASTME1853M-2004
【标准状态】:现行
【国别】:
【发布日期】:2004
【实施或试行日期】:
【发布单位】:美国材料与试验协会(US-ASTM)
【起草单位】:E47.02
【标准类型】:(Guide)
【标准水平】:()
【中文主题词】:毒物;遗传学;有机化合物;测量;感应
【英文主题词】:Ah-receptor;benzo[a]pyrene;biomarker;carcinogenic;coplanarorganiccompound;CYP1A;dioxin;induction;P4501A;reportergenesystem;TCDD;toxic
【摘要】:ThecompoundsthatbindtotheAh-receptorandinduceCYP1Ahaveoftenbeenshowntobeeithermoretoxicorcarcinogenic,orboth,thanotherorganiccompounds.Dioxins,furans,andPCBshavebeenshowntobioconcentrateinexposedorganismsandbiomagnifyinthefoodweb(seeGuideE1023).Testingwithbirds,mammals,andfishspecieshasshownthatexposuretothesecompoundscanproducephysiological,reproductiveandhistopathologicaleffects(12,13).Concernforthepossiblecontaminationofwater,food,wildlife,soil,andaquaticsedimentfromthesecompoundshasledtotherequirementforanalyticalchemicalanalysesofagreatmanyenvironmentalsamples.UseofascreeningtoolsuchasthisHumanReporterGeneSystem(HRGS)willallowidentificationofsignificantlycontaminatedsamples.Thesemethodswillaidinthecost-effectiveseparationofhighprioritysamplesfromthosethatdonotrequirefurthercostlychemicalcharacterization.1.1ThisguidecoverstherecommendedguidelinesforperformingatestforpresenceoforganiccompoundsthatbindtotheAhReceptorandinducetheCYP1Alocusonthevertebratechromosome.Underappropriatetestconditions,inductionofCYP1Aisevidencethatthecellshavebeenexposedtooneormoreofthesexenobioticorganiccompoundsthatincludedioxins,furans,coplanarPCBs,andseveralpolycyclicaromatichydrocarbons(PAHs).DetectionofinductionhasbeenmadesimpleandrapidbythestableintegrationofthefireflyplasmidsuchthatAh-receptorbindingresultsintheproductionofluciferase.Luciferaseproductionisafunctionofboththepotencyofthecompound(s)andtheconcentration.ThistypeofHumanReporterGeneSystem(HRGS)hasshownconcentration-responserelationshipsusing2,3,7,8-TCDD,5coplanarPCBs,andseveralpolycyclicaromatichydrocarbons(PAHs)(1-3).Thisguidedescribestestconditionsunderwhichsolventextractsofenvironmentalsamples(water,tissue,soil,orsediments)maybetestedforthepresenceofCYP1A-inducingorganiccompounds.1.2Thetestprocedurespresentedinthisguidehavebeenpublishedpreviously(4,5)andestablishedasEPAMethod4425(6).Thesereferencesshouldbeconsultedtoobtaindetailsregardingtheconstructionandmaintenanceofthecellline,andtheresponseofthecellstovariousorganicsubstances.1.3Alllaboratoryhealthandsafetyproceduresshouldbefollowed.Thisincludestheuseofglasses,gloves,andotherprotectiveclothing,whenhandlingthereagents.Informationontoxicity,handlingproceduresandwasteproceduresshouldbereviewedpriortouseofallchemicals.1.4Thisstandarddoesnotpurporttoaddressallofthesafetyconcerns,ifany,associatedwithitsuse.Itistheresponsibilityoftheuserofthisstandardtoestablishappropriatesafetyandhealthpracticesanddeterminetheapplicabilityofregulatorylimitationspriortouse.
【中国标准分类号】:A40
【国际标准分类号】:07_080
【页数】:9P.;A4
【正文语种】:
基本信息
标准名称: | 冷磨柠檬油 |
替代情况: | 被QB 1799-93代替 |
发布日期: | |
实施日期: | 1992-08-01 |
首发日期: | |
作废日期: | |
出版日期: | |
适用范围
没有内容
前言
没有内容
目录
没有内容
引用标准
没有内容
所属分类: 轻工 文化与生活用品 日用化工品 香精 香料